A newborn is noted to have low-set ears, micrognathia, and a cleft palate. The mother reports drinking alcohol daily during the first trimester. Which of the following best describes the embryologic period when these craniofacial abnormalities most likely developed?

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Weeks 4-8 of gestation. Craniofacial abnormalities associated with fetal alcohol syndrome typically develop during the critical period of facial development in weeks 4-8 of gestation. This is when the facial prominences and palatal shelves form, and exposure to teratogens during this period can lead to dysmorphic features including low-set ears, micrognathia, and cleft palate.

A newborn is noted to have low-set ears, micrognathia, and a cleft palate. The mother reports drinking alcohol daily during the first trimester. Which of the following best describes the embryologic period when these craniofacial abnormalities most likely developed?

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