HomeUSMLE Step 1 Medical PrepQuestion 5 of 10
USMLE Step 1 Medical PrepQuestion 5 / 10

A 3-year-old child has difficulty interacting with peers, demonstrates repetitive behaviors, and has delayed language development. Genetic testing reveals a mutation affecting synaptic proteins. Which of the following best describes the gene-environment interaction in this condition?

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✓ Correct answer: D. Genetic mutations affect neural circuit development, while environmental factors modify expression of symptoms Autism spectrum disorder often involves a complex interplay between genetic susceptibility and environmental factors. Genetic mutations affecting synaptic proteins can impact neural circuit development and connectivity, while early environmental exposures and experiences can influence how these genetic factors are expressed, potentially modifying the severity and presentation of the condition.

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