A neonate is being treated for congenital heart disease with chronic administration of spironolactone. This infant is at an increased risk for all the following electrolyte disturbances, EXCEPT:
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✓ Correct answer: C. HyperkalemiaAnswer: Hyperkalemia Spironolactone is an aldosterone antagonist diuretic that is used to treat conditions such as edema and heart failure in neonates. It works by blocking aldosterone receptors, which prevents sodium reabsorption but increases potassium retention. Hyponatremia, hypercalcemia, and hypovolemia are potential risks with the chronic use of spironolactone. However, hyperkalemia is a less common risk associated with its use.
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