A patient with hypothyroidism is prescribed levothyroxine (Synthroid). Which instruction is correct?

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Multiple choice — select the best answer

ATake it at bedtime with a glass of milk
BTake it with iron supplements for better absorption
CTake it with antacids to reduce GI upset
DTake it on an empty stomach 30-60 minutes before breakfast

✓ Correct answer: D. Take it on an empty stomach 30-60 minutes before breakfast Levothyroxine absorption is significantly reduced by food, calcium, iron, antacids, and proton pump inhibitors. It must be taken on an empty stomach 30-60 minutes before breakfast for optimal absorption.

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A patient with hypothyroidism is prescribed levothyroxine (Synthroid). Which instruction is correct?

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