A patient receiving chemotherapy develops severe nausea. The oncologist prescribes ondansetron. To which pharmacological class does ondansetron belong?

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ADopamine D2 receptor antagonist
BSerotonin 5-HT3 receptor antagonist
CNeurokinin-1 (NK1) receptor antagonist
DHistamine H1 receptor antagonist

✓ Correct answer: B. Serotonin 5-HT3 receptor antagonist Ondansetron (Zofran) is a selective 5-HT3 receptor antagonist that blocks serotonin at vagal afferents in the gut and at the chemoreceptor trigger zone, making it highly effective for chemotherapy-induced nausea and vomiting.

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A patient receiving chemotherapy develops severe nausea. The oncologist prescribes ondansetron. To which pharmacological class does ondansetron belong?

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