Which inflammatory mediator most directly stimulates osteoclastic alveolar bone resorption in periodontitis?

Which inflammatory mediator most directly

Multiple choice — select the best answer

AProstaglandin E2
BInterleukin-10
CImmunoglobulin A
DLysozyme

✓ Correct answer: A. Prostaglandin E2 Prostaglandin E2, along with IL-1 and TNF-alpha, upregulates the RANKL pathway driving osteoclast activity and bone loss; IL-10 is anti-inflammatory.

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Topic: Periodontology

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Which inflammatory mediator most directly stimulates osteoclastic alveolar bone resorption in periodontitis?

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