A 54-year-old female is diagnosed with an acute upper gastrointestinal bleed due to a duodenal ulcer. The patient presents with hematemesis and melena. Vital signs are BP 95/60, P 120, R 22, and $$SpO_{2}$$ 94%. After initial stabilization, which of the following medications is most appropriate to reduce gastric acid secretion and stabilize the ulcer?
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✓ Correct answer: D. Proton pump inhibitorsProton pump inhibitors are the first-line treatment for ulcer-related gastrointestinal bleeding as they help reduce gastric acid secretion, promoting ulcer healing. Antacids provide symptomatic relief but do not address the underlying acid secretion effectively. H2-receptor antagonists are less effective than proton pump inhibitors in treating acute gastrointestinal bleeding from ulcers. Sucralfate acts as a protective barrier at the ulcer site but does not significantly reduce acid secretion.
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