HomeAP US History Exam Prep IQuestion 4 of 10
AP US History Exam Prep IQuestion 4 / 10

The Columbian Exchange most directly resulted in which demographic change in the Americas after 1492?

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✓ Correct answer: A. Massive population decline among Native Americans due to disease European diseases such as smallpox, measles, and influenza, to which Native Americans had no immunity, caused catastrophic population decline. It is estimated that up to 90% of the indigenous population died within the first century of contact, fundamentally reshaping American demographics and societies.

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